Time to diagnosis in Cushing’s syndrome: A meta-analysis based on 5367 patients

Citation: Rubinstein, German and Osswald, Andrea and Hoster, Eva and Losa, Marco and Elenkova, Atanaska and Zacharieva, Sabina and Machado, Márcio Carlos and Hanzu, Felicia Alexandra and Zopp, Stephanie and Ritzel, Katrin and Riester, Anna and Braun, Leah Theresa and Kreitschmann-Andermahr, Ilonka and Storr, Helen L. and Bansal, Prachi and Barahona, María-José and Cosaro, Elisa and Dogansen, Sema Ciftci and Johnston, Philip C. and Santos de Oliveira, Ricardo and Raftopoulos, Christian and Scaroni, Carla and Valassi, Elena and van der Werff, Steven J.A. and Schopohl, Jochen and Beuschlein, Felix and Reincke, Martin: Time to diagnosis in Cushing’s syndrome: A meta-analysis based on 5367 patients. June 2019. Open Data LMU. 10.5282/ubm/data.153

Abstract

The time from first symptom to diagnosis of Cushing's syndrome is considered relevant for the severity of phenotype at presentation and long-term outcome. We therefore performed a systematic literature search to investigate relevant factors associated with a short time to diagnosis. The meta-analysis of 45 studies with 5560 patients showed significant differences for adrenal Cushing’s syndrome, Cushing’s disease and the ectopic Cushing’s syndrome. We did not find difference for gender, age or time of publication.

• Item Type: Data
• Contact Person: Rubinstein, German
• E-Mail of Contact: german.rubinstein at med.uni-muenchen.de
• Subjects: Medicine
• Dewey Decimal Classification: 600 Technology, Medicine > 610 Medical sciences and medicine